顧雅真助理教授 - 元培醫學影像暨放射技術系
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顧雅真助理教授

專任教師 - 醫學影像暨放射技術系(所)
教師姓名 顧雅真 (Ya-Chen Ko)
職稱 助理教授
學歷 國防醫學院生命科學研究所 博士
電話 03-5381183 ext.8911
研究室 放射二館R211
E-mail koyc@mail.ypu.edu.tw
專長 細胞生物學、腫瘤生物學
經歷  
相關研究計畫與論文

(A)參與主持的政府機構或產業單位研究計畫

  1. 低氧相關分子adrenomedullin與stanniocalcin 2在急性骨髓性白血病之生物與臨床意義的探討(NSC 100-2320-B-002-074-MY3),國科會,2011/08-2014/07。

(B)學術期刊論文

  1. Ko, Ya-Chen, Fang, Woei-Horng, Lin, Tsung-Chin, Hou, Hsin-An, Chen, Chien-Yuan, Tien, Hwei-Fang, Lin, Liang-In, “MicroRNA let-7a-3 gene methylation is associated with karyotyping, CEBPA promoter methylation, and survival in acute myeloid leukemia”Leukemia Research, Vol. 38, 2014, 05, pp. pp. 625-631.
  2. Ko, Ya-Chen, Chang, Chia-Ling, Chien, Hsiung-Fei, Wu, Ching-Hsiang, Lin, Liang-In, “Resveratrol enhances the expression of death receptor Fas/CD95 and induces differentiation and apoptosis in anaplastic large-cell lymphoma cells,”Cancer Letters, Vol. 309, No. 1, 2011, 10, pp. 46-53.
  3. Ko, Ya-Chen, Chien, Hsiung-Fei, Jiang-Shieh, Ya-Fen, Chang, Chiu-Yun, Pai, Man-Hui, Huang, Jian-Pei, Chen, Hui-Min, Wu, Ching-Hsiang, “Endothelial CD200 is heterogeneously distributed, regulated and involved in immune cell-endothelium interactions”Journal of Anatomy, Vol. 214, No. 1, 2009, 1, pp. 183-195.
  4. Chiu, Jeng-Jiann, Lee, Pei-Ling, Chen, Cheng-Nan, Lee, Chih-I, Chang, Shun-Fu, Chen, Li-Jing, Lien, Sheng-Chieh, Ko, Ya-Chen, Usami, Shunichi and Chien, Shu, “Shear Stress Increases ICAM-1 and Decreases VCAM-1 and E-selectin Expressions Induced by Tumor Necrosis Factor-[alpha] in Endothelial Cells,”Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 24, No. 1, 2004, 1, pp. 73-79.
  5. Chiu, Jeng-Jiann, Lee, Pei-Ling, Lee, Chih-I, Chen, Li-Jing, Chen, Cheng-Nan, Ko, Ya-Chen and Lien, Sheng-Chieh, “Shear Stress Attenuates Tumor Necrosis Factor-alpha-induced Monocyte Chemotactic Protein-1 Expressions in Endothelial Cells,”Chinese Journal of Physiology, Vol. 45, No. 4, 2002, pp. 169-176.
  6. Lin, Liang-In, Ke, Yuh-Fen, Ko, Ya-Chen and Lin, Jen-Kun, “Curcumin Inhibits SK-Hep-1 Hepatocellular Carcinoma Cell Invasion in Vitro and Suppresses Matrix Metalloproteinase-9 Secretion,”Oncology, Vol. 55, No. 4, 1998, 7, pp. 349-353.
  7. Ko, Ya-Chen , Langley, Keith E., Mendiaz, Elizabeth A., Parker, Vann P., Taylor, Shirley M. and DeClerck, Yves A., “The C-terminal Domain of Tissue Inhibitor of Metalloproteinases-2 is Required for Cell Binding but not for Antimetalloproteinase Activity,”Biochemical and Biophysical Research Communications, Vol. 236, No. 1, 1997, 7, pp. 100-105.

(C)研討會論文

  1. Wang, Annie, Lu, Jeng-Wei, Hou, Hsin-An, Chen, Chien-Yuan, Hu, Chung-Yi, Ou, Da-Liang, Ko, Ya-Chen, Tien, Hwei-Fang, Lin, Liang-In, “Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with internal tandem duplication of FLT3 (FLT3-ITD),”19th Congress of the European Hematology Association, Milano Congressi, Milan, Italy, 2014, 06, 12-2014, 06, 15.
  2. Ko, Ya-Chen, Teo, Min-Li, Hu, Chung-Yi, Chen, Yong-Sian, Chen, Chien-Yuan, Tien, Hwei-Fang, Lin, Liang-In, “MicroRNA Let-7a-3 Promoter Methylation is Associated with Karyotyping, CEBPA Promoter Methylation, and Survival in Acute Myeloid Leukemia ,”17th Congress of the European Hematology Association, RAI, Amsterdam, the Netherlands, 2012, 06, 14-2012, 06, 17.
  3. Ko, Ya-Chen, Jiang-Shieh, Ya-Fen, Chang, Chiu-Yun, Wei, I-Hua, Chien, Hsiung-Fei, Wu, Ching-Hsiang, “Heterogeneous Distribution and LPS Regulation of CD200 on Vascular Endothelium,”The 16th International Microscopy Congress, Sapporo Convention Center, Sapporo, Japan, 2006, 9, 3-2006, 9, 8.
  4. Chen, Cheng-Nan, Chang, Shun-Fu,Ko, Ya-Chen and Chiu, Jeng-Jiann, , “Effects of Disturbed Flow on Leukocyte Transendothelial Migration,,”The XIIIth International Vascular Biology Meeting, The Westin Harbour Castle Hotel, Toronto, Canada, 2004, 6.
  5. Chiu, Jeng-Jiann,Ko, Ya-Chen, Chen, Cheng-Nan, Yang, Cheng-Tsair, Chuang, Han-Sheng, Chien, Shu and Usami, Shunichi, , “Analysis of the Effect of Disturbed Flow on Monocytic Adhesion to Endothelial Cell,,”11th International Congress of Biorheology, Adora Golf Resort, Belek, Antalya, Turkey, 2002, 9, 22.

(D)專書及專書論文

  1. 姚學華、黃文濤、鄭成、蔡文翔、顧雅真,生物學實驗,永大書局,民國90年9月。
  2. 張林松、張澎心、張懿欣、陳敏惠、溫小娟、楊佳璋、顧雅真譯,人體生理學,文京圖書有限公司,民國87年8月。
(E)技術報告及其他著作
  1. 顧雅真, 內皮細胞CD200黏著分子的系統性分布、調控及功能之探討, 博士論文, 國防醫學院生命科學研究所, 2009, 6.

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