教師姓名

蘇茂源 (Mao-Yuan Su )

職稱

副教授

學歷

國立陽明大學醫學工程研究所 博士

電話

03-5381183 ext.7510

研究室

影醫館M510

E-mail

maoyuansu@mail.ypu.edu.tw

專長

磁振造影、放射物理學、保健物理學、醫學物理學       

經歷

師一級醫事放射師, 台大醫院影像醫學部 (1993.12－2025.12)

醫事技術長, 台大醫院影像醫學部 (2014.01－2020.12)

醫學教育委員, 台大醫院影像醫學部 (2014.01－2020.12)

考績委員, 台大醫院影像醫學部 (2014.01－2020.12)

題庫小組委員, 考選部 (2024.12－迄今)

醫學名詞審議委員,國家教育研究院 (2018.04－2020.04)

助理教授, 台大醫學院醫學系放射線科 (2012.09－2014.08)

講師, 台大醫學院醫學系放射線科 (2012.02－2012.08)

副理事長, 中華民國醫事放射師公會全國聯合會 (2016.11-2019.11)

常務理事, 台北市醫事放射師公會 (2012.04－2015.03)

理事, 台北市醫事放射師公會 (2010.04－2012.03)

理事, 中華民國醫事放射師公會全國聯合會 (2011.11－2013.10)

執行主編, 北市醫放雜誌 (2010.04－2012.03)

相關研究計畫與論文

Journal Papers (SCI):

1. Perfusion defects on thallium-201 scintigraphy in cardiac amyloidosis Hung YH, Yu AL, Ko CL, Chen YC, Su MY, Shun CT, Chao CC, Hsieh ST, Tseng PH, Lee MJ, Hsueh HW, Juang JJ, Tsai CH, Cheng MF, Lin YH. J Investig Med. 2025 Sep 24:10815589251384949.
2. Comprehensive cardiac magnetic resonance assessment of right ventricular and left atrial function for early diagnosis of heart failure with preserved ejection fraction Lin TT, Huang KC, Lin HH, Su MY, Lin LC, Lin LY, Wu CK. Eur Radiol. 2025 Aug 14.
3. Epicardial Adipose Tissue Is Associated With Geometry Alteration and Diastolic Dysfunction in Prediabetic Cardiomyopathy Hsu JC, Huang KC, Lin TT, Lee JK, Su MY, Juang JJ, Wu CK, Lin LY J Clin Endocrinol Metab. 2025 Apr 22;110(5):1478-1487.
4. Use of technetium-99m-pyrophosphate single-photon emission computed tomography/computed tomography in monitoring therapeutic changes of RNA interference therapeutics in patients with hereditary transthyretin amyloid cardiomyopathy Hung YH, Yu AL, Chen YC, Tsai CH, Su MY, Shun CT, Hsueh HW, Jyh-Ming Juang J, Lee MJ, Tseng PH, Hsu CH, Hsieh ST, Ko CL, Lin KP, Yu WC, Cheng MF, Chao CC, Lin YH. J Formos Med Assoc. 2025 Apr;124(4):333-339.
5. Impact of Tafamidis on [99mTc]Tc-pyrophosphate Scintigraphy in Ala97Ser Hereditary Transthyretin amyloid cardiomyopathy: significant initial reduction with stable Long-Term effects. Yu AL, Chen YC, Tsai CH, Chao CC, Su MY, Shun CT, Hsueh HW, Juang JJ, Lee MJ, Tseng PH, Hsieh ST, Cheng MF, Lin YH. Eur J Nucl Med Mol Imaging. 2025 Apr;52(5):1853-1863.
6. Effect of Tafamidis on Clinical and Functional Parameters in Transthyretin Amyloid Cardiomyopathy. Kao TW, Hung YH, Yu AL, Cheng MF, Su MY, Chao CC, Tsai CH, Lin YH. JACC Adv. 2025 Feb;4(2):101511.

7. Neck triangle nerve enlargement in hereditary transthyretin amyloidosis correlates with changes in the autonomic, cardiac, and gastrointestinal systems. Hsueh HW, Chao CC, Lin YH, Tseng PH, Su MY, Hsieh ST. J Intern Med. 2024 Dec;296(6):495-509.
8. Long-term results of stereotactic arrhythmia radioablation for refractory ventricular Arrhythmias-A Taiwanese population study. Ho LT, Chen JL, Hsu JC, Chan HM, Huang YC, Su MY, Kuo SH, Chang YC, Lin JL, Chen WJ, Lee WJ, Juang JJ, Lin LY J. Formos Med Assoc. 2024 Dec 2:S0929-6646(24)00550-3.
9. Diflunisal versus tafamidis on neuropathy and cardiomyopathy in hereditary transthyretin amyloidosis. Chao CC, Tzeng SR, Chiang MC, Hsueh HW, Hsieh WJ, Chao YC, Cheng MF, Lin YH, Su MY, Huang CH, Wang YS, Hsieh MF, Tseng PH, Hsieh ST Ann Clin Transl Neurol. 2024 Sep;11(9):2426-2438.
10. Tafamidis improves myocardial longitudinal strain in A97S transthyretin cardiac amyloidosis. Wu YA, Yu AL, Cheng MF, Lin LC, Lee MJ, Chou CH, Shun CT, Hsueh HW, Juang JJ, Tseng PH, Lin SP, Su MY, Chao CC, Hsieh ST, Tsai CH, Lin YH. Ther Adv Chronic Dis. 2024 Jan 11;15:20406223231222828.
11. Use of Technetium-99m-Pyrophosphate Single-Photon Emission Computed Tomography/Computed Tomography in Monitoring Therapeutic Changes of Eplontersen in Patients With Hereditary Transthyretin Amyloid Cardiomyopathy. Yu AL, Chen YC, Tsai CH, Wu YA, Su MY, Chou CH, Shun CT, Hsueh HW, Juang JJ, Lee MJ, Tseng PH, Hsu CH, Hsieh ST, Ko CL, Cheng MF, Chao CC, Lin YH. J Am Heart Assoc. 2024 Jan 16;13(2):e030512.

12. Tafamidis decreased cardiac amyloidosis deposition in patients with Ala97Ser hereditary transthyretin cardiomyopathy: a 12-month follow-up cohort study Tsai CH, Chao CC, Hsieh ST, Yu AL, Wu YA, Cheng MF, Lee MJ, Chou CH, Shun CT, Hsueh HW, Jyh-Ming Juang J, Tseng PH, Su MY, Lin YH Orphanet J Rare Dis. 2023 Sep 13;18(1):289.
13. Differentiating the Prognostic Determinants of Myocardial Steatosis for Heart Failure With Preserved Ejection Fraction by Cardiac Magnetic Resonance Imaging. Lin TT, Lee CK, Huang KC, Wu CK, Lee JK, Lan CW, Su MY, Hwang JJ, Wang YC, Lin LY J Am Heart Assoc. 2023 Sep 5;12(17):e027781.
14. Efficacy of Tafamidis in Patients with Ala97Ser Hereditary Transthyretin Cardiac Amyloidosis: A Six-Month Follow-Up Study. Tsai CH, Yu AL, Wu YA, Su MY, Cheng MF, Chou CH, Shun CT, Hsueh HW, Juang JJ, Lee MJ, Tseng PH, Hsieh ST, Chao CC, Lin YH. Acta Cardiol Sin. 2023 Jul;39(4):619-627.
15. Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension. Huang YS, Chen ZW, Lee WJ, Wu CK, Kuo PH, Hsu HH, Tang SY, Tsai CH, Su MY, Ko CL, Hwang JJ, Lin YH, Chang YC. Korean J Radiol. 2023 Apr;24(4):349-361.

16. Reverse cardiac remodelling and dysfunction in A97S transthyretin cardiac amyloidosis after tafamidis treatment. Wu YA, Tsai CH, Su MY, Chao CC, Cheng MF, Shun CT, Hsieh ST, Lin YH ESC Heart Fail. 2022 Dec;9(6):4335-4339.
17. Cardiomyopathy correlates to nerve damage in p.A117S late-onset transthyretin amyloid polyneuropathy. Lin YH, Hsueh HW, Su MY, Cheng MF, Chiang MC, Juang JJ, Kao YH, Chang KC, Feng FP, Hsieh ST, Chao CC. Ann Clin Transl Neurol. 2022 Sep;9(9):1359-1369.
18. First-in-human pilot trial of combined intracoronary and intravenous mesenchymal stem cell therapy in acute myocardial infarction. Hsiao LC, Lin YN, Shyu WC, Ho M, Lu CR, Chang SS, Wang YC, Chen JY, Lu SY, Wu MY, Li KY, Lin YK, Tseng WI, Su MY, Hsu CT, Tsai CK, Chiu LT, Chen CL, Lin CL, Hu KC, Cho DY, Tsai CH, Chang KC, Jeng LB. Front Cardiovasc Med. 2022 Aug 9;9:961920.

19. Applying Compressed Sensing Volumetric Interpolated Breath-Hold Examination and Spiral Ultrashort Echo Time Sequences for Lung Nodule Detection in MRI. Huang YS, Niisato E, Su MY, Benkert T, Chien N, Chiang PY, Lee WJ, Chen JS, Chang YC. Diagnostics (Basel). 2021 Dec 31;12(1):93.
20. Detecting small pulmonary nodules with spiral ultrashort echo time sequences in 1.5 T MRI. Huang YS, Niisato E, Su MY, Benkert T, Hsu HH, Shih JY, Chen JS, Chang YC. MAGMA. 2021 Jun;34(3):399-409.
21. First Asian population study of stereotactic body radiation therapy for ventricular arrhythmias. Ho LT, Chen JL, Chan HM, Huang YC, Su MY, Kuo SH, Chang YC, Lin JL, Chen WJ, Lee WJ, Lin LY. Sci Rep. 2021 May 14;11(1):10360.
22. Artificial Intelligence Aids Cardiac Image Quality Assessment for Improving Precision in Strain Measurements. Huang KC, Huang CS, Su MY, Hung CL, Ethan Tu YC, Lin LC, Hwang JJ. JACC Cardiovasc Imaging. 2021 Feb;14(2):335-345.

23. CMR-derived ECVs vary with myocardial region and associate with the regional wall thickness. Su MY, Hou KY, Liu MH, Lin TM, Juang JJ, Lin LY, Wu CK, Yu HY, Yang SC, Huang YS, Niisato E, Chang YC. Sci Rep. 2020 Dec 1;10(1):20965.
24. Is a timely assessment of the hematocrit necessary for cardiovascular magnetic resonance-derived extracellular volume measurements? Su MY, Huang YS, Niisato E, Chow K, Juang JJ, Wu CK, Yu HY, Lin LY, Yang SC, Chang YC. J Cardiovasc Magn Reson. 2020 Nov 30;22(1):77.
25. Long-term outcomes and left ventricular diastolic function of sarcomere mutation-positive and mutation-negative patients with hypertrophic cardiomyopathy: a prospective cohort study. Chen CJ, Su MY, Liao YC, Chang FL, Wu CK, Lin LY, Chen YS, Lin YH, Hwang JJ, Yu SL, Kao HL, Chen WJ, Lu TP, Shih CY, Yeh SS, Yang DH, Lai LP, Juang JJ Eur Heart J Cardiovasc Imaging. 2020 Nov 22:jeaa317.
26. Biventricular myocardial adaptation in patients with repaired tetralogy of Fallot: Mechanistic insights from magnetic resonance imaging tissue phase mapping. Chang MC, Wu MT, Weng KP, Chien KJ, Lin CC, Su MY, Lin KL, Chang MH, Peng HH PLoS One. 2020 Aug 11;15(8):e0237193.
27. Improving patient safety during intrahospital transportation of mechanically ventilated patients with critical illness. Lin SJ, Tsan CY, Su MY, Wu CL, Chen LC, Hsieh HJ, Hsiao WL, Cheng JC, Kuo YW, Jerng JS, Wu HD, Sun JS. BMJ Open Qual. 2020 Apr;9(2):e000698.
28. Myocardial adipose deposition and the development of heart failure with preserved ejection fraction. Wu CK, Lee JK, Hsu JC, Su MY, Wu YF, Lin TT, Lan CW, Hwang JJ, Lin LY Eur J Heart Fail. 2020 Mar;22(3):445-454.

29. Effect of Empagliflozin on Cardiac Function, Adiposity, and Diffuse Fibrosis in Patients with Type 2 Diabetes Mellitus. Hsu JC, Wang CY, Su MY, Lin LY, Yang WS. Sci Rep. 2019 Oct 25;9(1):15348.
30. Empirical Mode Decomposition and Monogenic Signal-Based Approach for Quantification of Myocardial Infarction From MR Images Tran TT, Pham VT, Lin C, Yang HW, Wang YH, Shyu KK, Tseng WI, Su MY, Lin LY, Lo MT IEEE J Biomed Health Inform. 2019 Mar;23(2):731-743.

31. Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients Wu CK, Su MY, Wu YF, Hwang JJ, Lin LY J Clin Med. 2018 Nov 8;7(11):427.
32. Left ventricular regional myocardial motion and twist function in repaired tetralogy of Fallot evaluated by magnetic resonance tissue phase mapping. Chang MC, Wu MT, Weng KP, Su MY, Menza M, Huang HC, Peng HH Eur Radiol. 2018 Jan;28(1):104-114.

33. Evolutional change in epicardial fat and its correlation with myocardial diffuse fibrosis in heart failure patients. Wu CK, Tsai HY, Su MY, Wu YF, Hwang JJ, Lin JL, Lin LY, Chen JJ J Clin Lipidol. 2017 Nov-Dec;11(6):1421-1431.
34. The extent of edema and tumor synchronous invasion into the subventricular zone and corpus callosum classify outcomes and radiotherapy strategies of glioblastomas. Liang HT, Chen WY, Lai SF, Su MY, You SL, Chen LH, Tseng HM, Chen CM, Kuo SH, Tseng WI Radiother Oncol. 2017 Nov;125(2):248-257.
35. The relationship among cardiac structure, dietary salt and aldosterone in patients with primary aldosteronism. Hung CS, Wu XM, Chen CW, Chen YH, Wu VC, Liao CW, Chang YY, Yen RF, Lu CC, Su MY, Liu KL, Chang CC, Liu LD, Wu KD, Lin YH; TAIPAI Study Group Oncotarget. 2017 Apr 28;8(42):73187-73197.

36. Clinical feasibility of Gd-EOB-DTPA-enhanced MR imaging for assessing liver function: validation with ICG tests and parenchymal cell volume. Chang CC, Huang HC, Liu KL, Wu YM, Lee JJ, Jiang SF, Su MY. Clin Imaging. 2016 Jul-Aug;40(4):797-800.
37. Introduction to Cardiovascular Magnetic Resonance: Technical Principles and Clinical Applications. Tseng WY, Su MY, Tseng YH. Acta Cardiol Sin. 2016 Mar;32(2):129-44.
38. Endocardial Remodeling in Heart Failure Patients with Impaired and Preserved Left Ventricular Systolic Function--A Magnetic Resonance Image Study. Lin LY, Su MY, Pham VT, Tran TT, Wang YH, Tseng WY, Lo MT, Lin JL Sci Rep. 2016 Feb 15;6:20868.
39. Myocardial Regional Interstitial Fibrosis is Associated With Left Intra-Ventricular Dyssynchrony in Patients With Heart Failure: A Cardiovascular Magnetic Resonance Study. Lin LY, Wu CK, Juang JM, Wang YC, Su MY, Lai LP, Hwang JJ, Chiang FT, Tseng WY, Lin JL Sci Rep. 2016 Feb 5;6:20711.

40. Galectin-3 level and the severity of cardiac diastolic dysfunction using cellular and animal models and clinical indices. Wu CK, Tsai HY, Su MY, Wu YF, Hwang JJ, Lin JL, Chen JJ, Liu FT, Tsai CT Sci Rep. 2015 Nov 19;5:17007.
41. Improvement of Cerebral Glucose Metabolism in Symptomatic Patients With Carotid Artery Stenosis After Stenting. Kao HL, Lin MS, Wu WC, Tseng WY, Su MY, Chen YF, Chiu MJ, Wang SY, Yang WS, Tzen KY, Wu YW, Chen MF Clin Nucl Med. 2015 Sep;40(9):701-7.
42. Pericardial fat is associated with ventricular tachyarrhythmia and mortality in patients with systolic heart failure. Wu CK, Tsai HY, Su MY, Wu YF, Hwang JJ, Tseng WY, Lin JL, Lin LY Atherosclerosis. 2015 Aug;241(2):607-614.
43. CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction. Hsu WT, Jui HY, Huang YH, Su MY, Wu YW, Tseng WY, Hsu MC, Chiang BL, Wu KK, Lee CM Cell Transplant. 2015;24(7):1313-28.
44. MRI evaluation of the adaptive response of the contralateral kidney following nephrectomy in patients with renal cell carcinoma. Su MY, Huang KH, Chang CC, Wu VC, Wu WC, Liu KL, Tseng WY J Magn Reson Imaging. 2015 Mar;41(3):822-8.

45. CMR-verified diffuse myocardial fibrosis is associated with diastolic dysfunction in HFpEF. Su MY, Lin LY, Tseng YH, Chang CC, Wu CK, Lin JL, Tseng WY JACC Cardiovasc Imaging. 2014 Oct;7(10):991-7.
46. Connective tissue growth factor and cardiac diastolic dysfunction: human data from the Taiwan diastolic heart failure registry and molecular basis by cellular and animal models. Wu CK, Wang YC, Lee JK, Chang SN, Su MY, Yeh HM, Su MJ, Chen JJ, Chiang FT, Hwang JJ, Lin JL, Tsai CT. Eur J Heart Fail. 2014 Feb;16(2):163-72.
47. Conductive channels identified with contrast-enhanced MR imaging predict ventricular tachycardia in systolic heart failure. Lin LY, Su MY, Chen JJ, Lai LP, Hwang JJ, Tseng CD, Chen YS, Yu HY, Tseng WY, Lin JL. JACC Cardiovasc Imaging. 2013 Nov;6(11):1152-9.
48. Circulating biomarkers of collagen type I metabolism mark the right ventricular fibrosis and adverse markers of clinical outcome in adults with repaired tetralogy of Fallot. Chen CA, Tseng WY, Wang JK, Chen SY, Ni YH, Huang KC, Ho YL, Chang CI, Chiu IS, Su MY, Yu HY, Lin MT, Lu CW, Wu MH. Int J Cardiol. 2013 Sep 10;167(6):2963-8.

49. Contrast-enhanced MRI index of diffuse myocardial fibrosis is increased in primary aldosteronism. Su MY, Wu VC, Yu HY, Lin YH, Kuo CC, Liu KL, Wang SM, Chueh SC, Lin LY, Wu KD, Tseng WY J Magn Reson Imaging. 2012 Jun;35(6):1349-55.

50. Renal perfusion 3-T MR imaging: a comparative study of arterial spin labeling and dynamic contrast-enhanced techniques. Wu WC, Su MY, Chang CC, Tseng WY, Liu KL Radiology. 2011 Dec;261(3):845-53.
51. Exercise training increases myocardial perfusion in residual viable myocardium within infarct zone. Su MY, Lee BC, Yu HY, Wu YW, Chu WC, Tseng WY J Magn Reson Imaging. 2011 Jul;34(1):60-8.

52. Sequential changes of myocardial microstructure in patients postmyocardial infarction by diffusion-tensor cardiac MR: correlation with left ventricular structure and function. Wu MT, Su MY, Huang YL, Chiou KR, Yang P, Pan HB, Reese TG, Wedeen VJ, Tseng WY. Circ Cardiovasc Imaging. 2009 Jan;2(1):32-40, 6 p following 40.

53. Perfusion of residual viable myocardium in nontransmural infarct zone after intervention: MR quantitative myocardial blood flow measurement. Su MY, Lee BC, Wu YW, Yu HY, Chu WC, Tseng WY Radiology. 2008 Dec;249(3):820-8.
54. Effect of cardiac rehabilitation on myocardial perfusion reserve in postinfarction patients. Lee BC, Chen SY, Hsu HC, Su MY, Wu YW, Chien KL, Tseng WY, Chen MF, Lee YT Am J Cardiol. 2008 May 15;101(10):1395-402.

55. First-pass myocardial perfusion cardiovascular magnetic resonance at 3 Tesla. Su MY, Yang KC, Wu CC, Wu YW, Yu HY, Tseng RY, Tseng WY J Cardiovasc Magn Reson. 2007;9(4):633-44.

56. Diffusion tensor magnetic resonance imaging mapping the fiber architecture remodeling in human myocardium after infarction: correlation with viability and wall motion. Wu MT, Tseng WY, Su MY, Liu CP, Chiou KR, Wedeen VJ, Reese TG, Yang CF Circulation. 2006 Sep 5;114(10):1036-45.

57. Mitral tetrahedron as a geometrical surrogate for chronic ischemic mitral regurgitation. Yu HY, Su MY, Chen YS, Lin FY, Tseng WY Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1218-25.
58. Functional mitral regurgitation in chronic ischemic coronary artery disease: analysis of geometric alterations of mitral apparatus with magnetic resonance imaging. Yu HY, Su MY, Liao TY, Peng HH, Lin FY, Tseng WY J Thorac Cardiovasc Surg. 2004 Oct;128(4):543-51.

專業書籍

兒童心臟學第二版 - 第13章 心臟血管磁振造影簡介（曾文毅、蘇茂源）

肥厚型心肌病變攻略 - Topic 4 心血管磁共振造影在肥厚性心肌病變隻角色 （蘇茂源）

研究計畫